Warning
Please note that VirtualBox 6.1 is not compatible with Genymotion Desktop 3.0. If you are using this version, please remove it and downgrade to VirtualBox 6.0.4 or 6.0.18.
You can find it here: https://www.virtualbox.org/wiki/Download_Old_Builds_6_0
This error may be caused by Hyper-V which interferes with VirtualBox. Please make sure Hyper-V is disabled when using Genymotion Desktop. See Genymotion Desktop and Hyper-V (Windows 8/8.1/10) for instructions.
Also, VPNs interferes with Genymotion and VirtualBox. If you use a VPN, please read Genymotion Desktop and VPN for more details.
If none of the above apply to you, please try the following:
If you have several Host-only interface adapters, you need to repeat this to each of them.
If it still does not work, please try this:
If none of the above works, try to remove and re-install VirtualBox.